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Anti-Human SEC24C Polyclonal Antibody (HD071014)

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概述
货号HD071014
品牌abinScience
描述
Anti-Human SEC24C Polyclonal Antibody (HD071014) is a rabbit polyclonal antibody detecting SEC24C. Suitable for Human.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SEC24C (Asp324-Ser1094).
靶标KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P53992
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5.

1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955
2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046
3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296
4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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