

| 货号 | HD071014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SEC24C Polyclonal Antibody (HD071014) is a rabbit polyclonal antibody detecting SEC24C. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SEC24C (Asp324-Ser1094). | ||||||||
| 靶标 | KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P53992 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5. 1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955 2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046 3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296 4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317 | ||||||||
| Note | For research use only |

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