

| 货号 | HC987014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLURP2 Polyclonal Antibody (HC987014) is a rabbit polyclonal antibody detecting SLURP2. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLURP2 (Ile23-Asp97). | ||||||||
| 靶标 | SLURP-2, SLURP2, Secreted LY6/PLAUR domain-containing protein 2, Secreted Ly-6/uPAR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P0DP57 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) is a ~10 kDa protein. Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner. | ||||||||
| Note | For research use only |

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