

| 货号 | HC806014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLC38A3 Polyclonal Antibody (HC806014) is a rabbit polyclonal antibody detecting SLC38A3. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC38A3 (Lys234-Asn323). | ||||||||
| 靶标 | G17, N-system amino acid transporter 1, NAT1, Na(+)-coupled neutral amino acid transporter 3, SLC38A3, SN1, SNAT3, Sodium-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q99624 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Sodium-coupled neutral amino acid transporter 3 (SLC38A3) is a ~55 kDa protein. Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine. The transport activity is specific for L-glutamine, L-histidine and L-asparagine. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions. 1. Fei, YJ. et al. (2000) The Journal of biological chemistry 275, 23707-17. PMID: 10823827 | ||||||||
| Note | For research use only |

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