Anti-Mouse LpPLA2/PLA2G7/PAF-AH Polyclonal Antibody (MC293014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

MC293014

品牌

abinScience

描述

Anti-Mouse LpPLA2/PLA2G7/PAF-AH Polyclonal Antibody (MC293014) is a rabbit polyclonal antibody detecting PLA2G7. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse LpPLA2/PLA2G7/PAF-AH (Phe22-Asn440).

靶标

1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, EC:3.1.1.47, Group-VIIA phospholipase A2, LDL-PLA(2), LDL-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, PAFAH, PLA2G7, Platelet-activating factor acetylhydrolase, gVIIA-PLA2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q60963

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Platelet-activating factor acetylhydrolase (LpPLA2/PLA2G7) is a ~49 kDa protein. Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response. At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells.

1. Stafforini, DM. et al. (1999) The Journal of biological chemistry 274, 7018-24. PMID: 10066756

2. Gardner, AA. et al. (2008) The Journal of biological chemistry 283, 17099-106. PMID: 18434304

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse LpPLA2/PLA2G7/PAF-AH Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LpPLA2/PLA2G7/PAF-AH Polyclonal Antibody (MC293014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LpPLA2/PLA2G7/PAF-AH Polyclonal Antibody (MC293014)

概述

图片

参考文献

产品说明书

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