Anti-Mouse CD150/SLAMF1 Polyclonal Antibody (MC275014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

MC275014

品牌

abinScience

描述

Anti-Mouse CD150/SLAMF1 Polyclonal Antibody (MC275014) is a rabbit polyclonal antibody detecting SLAMF1. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Mouse CD150/SLAMF1 (Asp31-Cys232).

靶标

CD150, CDw150, IPO-3, SLAM, SLAM family member 1, SLAMF1, Signaling lymphocytic activation molecule

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9QUM4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Signaling lymphocytic activation molecule (CD150/SLAMF1) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

1. Howie, D. et al. (2002) Blood 100, 2899-907. PMID: 12351401

2. Aversa, G. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 4036-44. PMID: 9126961

3. Latour, S. et al. (2001) Nature immunology 2, 681-90. PMID: 11477403

4. Cannons, JL. et al. (2004) Immunity 21, 693-706. PMID: 15539155

5. Chen, R. et al. (2006) Molecular and cellular biology 26, 5559-68. PMID: 16847311

6. Wang, N. et al. (2004) The Journal of experimental medicine 199, 1255-64. PMID: 15123745

7. Yusuf, I. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 190-202. PMID: 20525889

8. Wang, N. et al. (2006) American journal of respiratory cell and molecular biology 35, 206-10. PMID: 16528012

9. Griewank, K. et al. (2007) Immunity 27, 751-62. PMID: 18031695

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse CD150/SLAMF1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD150/SLAMF1 Polyclonal Antibody (MC275014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD150/SLAMF1 Polyclonal Antibody (MC275014)

概述

图片

参考文献

产品说明书

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