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Anti-Human CCT8 Polyclonal Antibody (HC197014)

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规格:
  • 50ug
  • 100ug
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概述
货号HC197014
品牌abinScience
描述
Anti-Human CCT8 Polyclonal Antibody (HC197014) is a rabbit polyclonal antibody detecting CCT8. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CCT8 (Glu26-Asp522).
靶标C21orf112, CCT-theta, CCT8, CCTQ, Chaperonin containing T-complex polypeptide 1 subunit 8, EC:3.6.1.-, KIAA0002, Renal carcinoma antigen NY-REN-15, T-complex protein 1 subunit theta, TCP-1-theta
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P50990
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

T-complex protein 1 subunit theta (CCT8) is a ~59 kDa protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.

1. Freund, A. et al. (2014) Cell 159, 1389-403. PMID: 25467444
2. Gestaut, D. et al. (2022) Cell 185, 4770-4787.e20. PMID: 36493755
3. Kelly, JJ. et al. (2022) Nature structural & molecular biology 29, 420-429. PMID: 35449234
4. Liu, C. et al. (2023) Communications biology 6, 531. PMID: 37193829
5. Seo, S. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 1488-93. PMID: 20080638
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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