

| 货号 | HC197014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human CCT8 Polyclonal Antibody (HC197014) is a rabbit polyclonal antibody detecting CCT8. Suitable for Mouse and Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CCT8 (Glu26-Asp522). | ||||||||
| 靶标 | C21orf112, CCT-theta, CCT8, CCTQ, Chaperonin containing T-complex polypeptide 1 subunit 8, EC:3.6.1.-, KIAA0002, Renal carcinoma antigen NY-REN-15, T-complex protein 1 subunit theta, TCP-1-theta | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P50990 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | T-complex protein 1 subunit theta (CCT8) is a ~59 kDa protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. 1. Freund, A. et al. (2014) Cell 159, 1389-403. PMID: 25467444 2. Gestaut, D. et al. (2022) Cell 185, 4770-4787.e20. PMID: 36493755 3. Kelly, JJ. et al. (2022) Nature structural & molecular biology 29, 420-429. PMID: 35449234 4. Liu, C. et al. (2023) Communications biology 6, 531. PMID: 37193829 5. Seo, S. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 1488-93. PMID: 20080638 | ||||||||
| Note | For research use only |

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