

| 货号 | HC189014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human PMPCB Polyclonal Antibody (HC189014) is a rabbit polyclonal antibody detecting PMPCB. Suitable for Human, Rat, and Mouse.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PMPCB (Arg59-Asp489). | ||||||||
| 靶标 | Beta-MPP, EC:3.4.24.64, MPPB, Mitochondrial-processing peptidase subunit beta, P-52, PMPCB | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O75439 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Mitochondrial-processing peptidase subunit beta (PMPCB) is a ~54 kDa protein. Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. 1. Vögtle, FN. et al. (2018) American journal of human genetics 102, 557-573. PMID: 29576218 2. Greene, AW. et al. (2012) EMBO reports 13, 378-85. PMID: 22354088 | ||||||||
| Note | For research use only |

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