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Anti-Mouse SEMA4A Polyclonal Antibody (MA988014)

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概述
货号MA988014
品牌abinScience
描述
Anti-Mouse SEMA4A Polyclonal Antibody (MA988014) is a rabbit polyclonal antibody detecting SEMA4A. Suitable for Mouse.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse SEMA4A (Arg41-Cys546).
靶标SEMA4A, SEMAB, SEMB, Sema B, Semaphorin-4A, Semaphorin-B
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q62178
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Semaphorin-4A (SEMA4A) is a ~83 kDa protein. Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Regulates glutamatergic and GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2.

1. Toyofuku, T. et al. (2007) The EMBO journal 26, 1373-84. PMID: 17318185
2. Yukawa, K. et al. (2010) International journal of molecular medicine 25, 225-30. PMID: 20043131
3. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 29981480
4. Kumanogoh, A. et al. (2005) Immunity 22, 305-16. PMID: 15780988
5. Kumanogoh, A. et al. (2002) Nature 419, 629-33. PMID: 12374982
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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