Anti-G protein/Gαβγ Recombinant Nanobody (Nb35) (HX948013)

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100ug
1mg

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概述

货号	HX948013
品牌	abinScience
描述	Anti-G protein/Gαβγ Nanobody (Nb35) (HX948013) is a alpaca monoclonal antibody detecting G protein/Gαβγ. Suitable for Human.
种属反应性	Human
应用	Crystallography, Cryo-EM
宿主	Alpaca
同种型	VHH-His
克隆号	Nb35
克隆类型	Monoclonal
靶标	Adenylate cyclase-stimulating G alpha protein, EC:3.6.5.-, GNAS, GNAS1, GSP, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P63092
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gαβγ) is a ~45 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. 1. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 2. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 3. Thiele, S. et al. (2011) Human mutation 32, 653-60. PMID: 21488135 4. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 5. Farfel, Z. et al. (1996) The Journal of biological chemistry 271, 19653-5. PMID: 8702665 6. Warner, DR. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 4268-72. PMID: 10200251
Note	For research use only

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参考文献

产品说明书

Anti-G protein/Gαβγ Recombinant Nanobody (Nb35).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-G protein/Gαβγ Recombinant Nanobody (Nb35) (HX948013)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-G protein/Gαβγ Recombinant Nanobody (Nb35) (HX948013)

概述

图片

参考文献

产品说明书

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