

| 货号 | MX041014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse F2RL1 Polyclonal Antibody (MX041014) is a rabbit polyclonal antibody detecting Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2. Suitable for Mouse.
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse F2RL1 (Ser39-Gly73&Met214-Leu237&Ser350-Tyr399). | ||||||||
| 靶标 | Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P55086 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Proteinase-activated receptor 2 (F2RL1) is a ~44 kDa protein. Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2r/Par1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation. 1. Borensztajn, K. et al. (2008) The American journal of pathology 172, 309-20. PMID: 18202198 | ||||||||
| Note | For research use only |

Lane 1: Mouse kidney lysate



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