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Anti-Mouse F2RL1 Polyclonal Antibody (MX041014)

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规格:
  • 50ug
  • 100ug
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号MX041014
品牌abinScience
描述
Anti-Mouse F2RL1 Polyclonal Antibody (MX041014) is a rabbit polyclonal antibody detecting Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2. Suitable for Mouse.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse F2RL1 (Ser39-Gly73&Met214-Leu237&Ser350-Tyr399).
靶标Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P55086
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Proteinase-activated receptor 2 (F2RL1) is a ~44 kDa protein. Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2r/Par1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation.

1. Borensztajn, K. et al. (2008) The American journal of pathology 172, 309-20. PMID: 18202198
NoteFor research use only
图片
  • Western blot

    Lane 1: Mouse kidney lysate

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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