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Anti-PDXK Polyclonal Antibody (HT485014)

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概述
货号HT485014
品牌abinScience
描述
Anti-PDXK Polyclonal Antibody (HT485014) is a rabbit polyclonal antibody detecting PDXK in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Ovis aries, and Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human PDXK (Gln29-Lys253).
靶标Pyridoxine kinase, Pyridoxal kinase, C21orf97, PDXK, PNK, PKH, C21orf124
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号O00764
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Pyridoxal kinase (PDXK) is a ~35 kDa protein. Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.

1. Lee, HS. et al. (2000) Molecules and cells 10, 452-9. PMID: 10987144
2. Musayev, FN. et al. (2007) Protein science : a publication of the Protein Society 16, 2184-94. PMID: 17766369
3. Gandhi, AK. et al. (2009) Biochemical and biophysical research communications 381, 12-5. PMID: 19351586
4. Chelban, V. et al. (2019) Annals of neurology 86, 225-240. PMID: 31187503
5. Hanna, MC. et al. (1997) The Journal of biological chemistry 272, 10756-60. PMID: 9099727
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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