

| 货号 | ICH6071 | ||||
|---|---|---|---|---|---|
| 品牌 | IchorBio | ||||
| 描述 |
Vandortuzumab Biosimilar - Research Grade (ICH6071) is a CHO (IgG1 - kappa) antibody targeting STEAP1. Reactive with Human. Validated for Functional Assays, Flow Cytometry, ImmunoCytoChemistry, Immunohistochemistry, ImmunoPrecipitation, RIA.
Highlights
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| 种属反应性 | Human | ||||
| 应用 | Functional Assays, Flow Cytometry, ImmunoCytoChemistry, Immunohistochemistry, ImmunoPrecipitation, RIA | ||||
| 宿主 | CHO | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG1 - kappa | ||||
| 经测试应用 | Functional Assays, Flow Cytometry, ImmunoCytoChemistry, Immunohistochemistry, ImmunoPrecipitation, RIA | ||||
| 靶标 | STEAP1 | ||||
| 特异性 | STEAP1 | ||||
| 内毒素水平 | <1 EU/mg | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. | ||||
| Accession号 | Q9UHE8 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | Sterile, preservative-free, solution in PBS. BSA and Azide free. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 运输 | Blue ice | ||||
| 产品使用信息 |
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| 稳定性和存储 | Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles. | ||||
| 规格 | Size: 5mg | ||||
| 背景 | Useful as a positive control in STEAP1 binding/internalisation assays, a comparator for novel anti-STEAP1 candidates/ADCs, and a scaffold for ADC/bispecific development. STEAP1 is a cell-surface metalloreductase highly overexpressed in prostate cancer with limited normal-tissue expression, making it an attractive ADC and T-cell-engaging bispecific target for selectively reaching tumour cells while sparing healthy tissue. Cell-surface metalloreductase highly overexpressed in prostate cance | ||||
| Note | For research use only | ||||
| Isotype Control | ICH2254 |

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