



| 货号 | HW393013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ICC, IHC, WB | ||||
| 同种型 | IgG2a | ||||
| 克隆号 | N331/19 | ||||
| 靶标 | D(3) dopamine receptor, Dopamine D3 receptor, DRD3 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P35462 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | D(3) dopamine receptor (DRD3/Dopamine D3 receptor) is a ~44 kDa protein. Dopamine receptor that is primarily expressed in limbic areas of the brain and is involved in the modulation of cognitive, emotional, and endocrine functions. Plays a key role in regulating neuronal signaling pathways associated with motivation, reward, and behavior. Coupled to G(i)/G(o) proteins; activation leads to inhibition of adenylate cyclase and decreased intracellular cAMP levels. Involved in the control of locomotor activity and implicated in several neuropsychiatric disorders, including schizophrenia and substance use disorders. Promotes cell proliferation through MAP kinase signaling. 1. Osugo, M. et al. (2025) Nature communications 16, 1852. PMID: 39984436 2. Zaworski, PG. et al. (1999) British journal of pharmacology 128, 1181-8. PMID: 10578130 3. Villar, VA. et al. (2009) The Journal of biological chemistry 284, 21425-34. PMID: 19520868 4. Barroso-Chinea, P. et al. (2020) Autophagy 16, 1279-1295. PMID: 31538542 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307) |

SEC-HPLC detection for Anti-Human DRD3 Antibody (N331/19).

SDS-PAGE for Anti-Human DRD3 Antibody (N331/19).





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