

| 货号 | HF524014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-GLRX3 Polyclonal Antibody (HF524014) is a rabbit polyclonal antibody detecting GLRX3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLRX3 (Val10-Ser117). | ||||||||
| 靶标 | PKCq-interacting protein, PKC-theta-interacting protein, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, GLRX3, Thioredoxin-like protein 2, TXNL2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O76003 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutaredoxin-3 (GLRX3) is a ~37 kDa protein. Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. 1. Banci, L. et al. (2015) Journal of the American Chemical Society 137, 16133-43. PMID: 26613676 2. Frey, AG. et al. (2016) The Journal of biological chemistry 291, 22344-22356. PMID: 27519415 3. Haunhorst, P. et al. (2013) Molecular biology of the cell 24, 1895-903. PMID: 23615448 | ||||||||
| Note | For research use only. |

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