

| 货号 | HF014014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-GLUD1 Polyclonal Antibody (HF014014) is a rabbit polyclonal antibody detecting GLUD1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Hylobates lar.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLUD1 (Asp334-Thr556). | ||||||||
| 靶标 | GLUD1, GDH 1, Glutamate dehydrogenase 1, mitochondrial, GLUD | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P00367 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutamate dehydrogenase 1, mitochondrial (GLUD1) is a ~61 kDa protein. Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. 1. Plaitakis, A. et al. (2000) Journal of neurochemistry 75, 1862-9. PMID: 11032875 2. Smith, TJ. et al. (2001) Journal of molecular biology 307, 707-20. PMID: 11254391 3. Choi, MM. et al. (2005) FEBS letters 579, 4125-30. PMID: 16023112 4. Haigis, MC. et al. (2006) Cell 126, 941-54. PMID: 16959573 5. MacMullen, C. et al. (2001) The Journal of clinical endocrinology and metabolism 86, 1782-7. PMID: 11297618 6. Stanley, CA. et al. (1998) The New England journal of medicine 338, 1352-7. PMID: 9571255 | ||||||||
| Note | For research use only. |

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