

| 货号 | HY413014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human MPO (Val165-Gly278). | ||||||||
| 靶标 | Myeloperoxidase, MPO | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P05164 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. 1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160 2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-MPO polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate



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