

| 货号 | HY427014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-KRT8/CK-8 Polyclonal Antibody (HY427014) is a rabbit polyclonal antibody detecting KRT8 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Human, Rat, and Xenopus laevis.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human KRT8/CK-8 (Gln90-Gln236). | ||||||||
| 靶标 | Type-II keratin Kb8, CYK8, Keratin-8, KRT8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, K8 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P05787 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Keratin, type II cytoskeletal 8 (KRT8/CK-8) is a ~53 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. 1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019 | ||||||||
| Note | For research use only. |

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