

| 货号 | HY099014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-CTSL Polyclonal Antibody (HY099014) is a rabbit polyclonal antibody detecting CTSL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTSL (Ala114-Thr288). | ||||||||
| 靶标 | CTSL1, MEP, Procathepsin L, Major excreted protein, Cathepsin L1, CTSL | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P07711 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Procathepsin L (CTSL) is a ~37 kDa protein. Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter. In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells. 1. Felbor, U. et al. (2000) The EMBO journal 19, 1187-94. PMID: 10716919 | ||||||||
| Note | For research use only. |

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