

| 货号 | HY149014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-NMB Polyclonal Antibody (HY149014) is a rabbit polyclonal antibody detecting NMB in ELISA, IHC, WB. Suitable for Human.
Highlights
| ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human NMB (Ala25-Lys121). | ||||||||
| 靶标 | NMB, Neuromedin-B | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P08949 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Neuromedin-B (NMB) is a ~13 kDa protein. Stimulates smooth muscle contraction. Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response. Contributes to induction of acute itch, possibly through activation of the NMBR receptor on dorsal root ganglion neurons. 1. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理