Anti-CALM1 Polyclonal Antibody (HY390014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HY390014

品牌

abinScience

描述

Anti-CALM1 Polyclonal Antibody (HY390014) is a rabbit polyclonal antibody detecting CALM1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Achlya klebsiana, and Agaricus bisporus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CALM1 (Ala2-Lys149).

靶标

CAM1, CALM1, CAM, CALM, Calmodulin-1

纯化方式

Purified by antigen affinity column.

Accession号

P0DP23

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Calmodulin-1 (CALM1) is a ~16 kDa protein. Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels.

1. Tsang, WY. et al. (2006) Molecular biology of the cell 17, 3423-34. PMID: 16760425

2. Reichow, SL. et al. (2013) Nature structural & molecular biology 20, 1085-92. PMID: 23893133

3. Boczek, NJ. et al. (2016) Circulation. Cardiovascular genetics 9, 136-146. PMID: 26969752

4. Yu, CC. et al. (2016) Heart rhythm 13, 1716-23. PMID: 27165696

5. Zhao, YG. et al. (2017) Molecular cell 67, 974-989.e6. PMID: 28890335

6. Wren, LM. et al. (2019) Circulation. Genomic and precision medicine 12, 375-385. PMID: 31454269

7. Alphonse, N. et al. (2022) Cell 185, 2354-2369.e17. PMID: 35568036

Note

For research use only.

图片

参考文献

产品说明书

Anti-CALM1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CALM1 Polyclonal Antibody (HY390014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CALM1 Polyclonal Antibody (HY390014)

概述

图片

参考文献

产品说明书

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