Anti-Human CCL2/MCP-1 Polyclonal Antibody (HY280014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HY280014

品牌

abinScience

描述

Anti-CCL2/MCP-1 Polyclonal Antibody (HY280014) is a rabbit polyclonal antibody detecting MCP-1 in ELISA, IHC, WB. Suitable for Human, Macaca fascicularis, Macaca mulatta, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CCL2/MCP-1 (Gln24-Thr99).

靶标

HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2

纯化方式

Purified by antigen affinity column.

Accession号

P13500

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171

2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439

3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883

4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247

5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182

6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674

7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human CCL2/MCP-1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CCL2/MCP-1 Polyclonal Antibody (HY280014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CCL2/MCP-1 Polyclonal Antibody (HY280014)

概述

图片

参考文献

产品说明书

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