Anti-CTLA-4 Polyclonal Antibody (HB651014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HB651014

品牌

abinScience

描述

Anti-CD152/CTLA4 Polyclonal Antibody (HB651014) is a rabbit polyclonal antibody detecting CD152 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD152/CTLA4 (Ala37-Asp161).

靶标

CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4

纯化方式

Purified by antigen affinity column.

Accession号

P16410

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

1. Schwartz, JC. et al. (2001) Nature 410, 604-8. PMID: 11279501

2. Stamper, CC. et al. (2001) Nature 410, 608-11. PMID: 11279502

3. Teft, WA. et al. (2006) Annual review of immunology 24, 65-97. PMID: 16551244

4. Linsley, PS. et al. (1991) The Journal of experimental medicine 174, 561-9. PMID: 1714933

5. Zheng, Y. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 1683-91. PMID: 18641304

6. Ramagopal, UA. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E4223-E4232. PMID: 28484017

Note

For research use only.

图片

参考文献

产品说明书

Anti-CTLA-4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CTLA-4 Polyclonal Antibody (HB651014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CTLA-4 Polyclonal Antibody (HB651014)

概述

图片

参考文献

产品说明书

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