

| 货号 | HB935014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-BDNF Polyclonal Antibody (HB935014) is a rabbit polyclonal antibody detecting BDNF in ELISA, IF, IHC, WB. Suitable for Human, Mouse, Dog, Cat, and Ailurus fulgens.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IF, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human BDNF (Arg128-Arg247). | ||||||||
| 靶标 | ProBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P23560 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Neurotrophic factor BDNF precursor form is a ~27 kDa protein. Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. 1. Mowla, SJ. et al. (2001) The Journal of biological chemistry 276, 12660-6. PMID: 11152678 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-BDNF polyclonal antibody at 1µg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse lung lysate
Lane 3: Mouse cerebellum lysate



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