Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014)

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概述
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参考文献
产品说明书

概述

货号

HB290014

品牌

abinScience

描述

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014) is a rabbit polyclonal antibody detecting Hu-antigen D in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Danio rerio, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human ELAVL4/HuD/Hu-antigen D (Val2-Ser380).

靶标

Paraneoplastic encephalomyelitis antigen HuD, HUD, Hu-antigen D, ELAVL4, PNEM, HuD, ELAV-like protein 4

纯化方式

Purified by antigen affinity column.

Accession号

P26378

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

ELAV-like protein 4 (ELAVL4/HuD) is a ~42 kDa protein. RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (UTR) of target mRNAs, including GAP43, VEGF, FOS, CDKN1A and ACHE mRNA. Many of the target mRNAs are coding for RNA-binding proteins, transcription factors and proteins involved in RNA processing and/or neuronal development and function. By binding to the mRNA 3'UTR, decreases mRNA deadenylation and thereby contributes to the stabilization of mRNA molecules and their protection from decay.

1. King, PH. (2000) Nucleic acids research 28, E20. PMID: 10710437

2. Beckel-Mitchener, AC. et al. (2002) The Journal of biological chemistry 277, 27996-8002. PMID: 12034726

3. Deschenes-Furry, J. et al. (2003) The Journal of biological chemistry 278, 5710-7. PMID: 12468554

4. Zhu, H. et al. (2006) Molecular biology of the cell 17, 5105-14. PMID: 17035636

5. Deschênes-Furry, J. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 665-75. PMID: 17234598

6. Liu, J. et al. (1995) Neurology 45, 544-50. PMID: 7898713

Note

For research use only.

图片

参考文献

产品说明书

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014)

概述

图片

参考文献

产品说明书

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