

| 货号 | HB949014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-ACVR2A Polyclonal Antibody (HB949014) is a rabbit polyclonal antibody detecting ACVR2A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human ACVR2A (Ala20-Pro135). | ||||||||
| 靶标 | ACVR2, ACTRIIA, ACTR-IIA, Activin receptor type IIA, ACVR2A, Activin receptor type-2A | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P27037 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Activin receptor type-2A (ACVR2A) is a ~57 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. 1. Renlund, N. et al. (2007) The Journal of endocrinology 195, 95-103. PMID: 17911401 2. Gray, PC. et al. (2000) The Journal of biological chemistry 275, 3206-12. PMID: 10652306 | ||||||||
| Note | For research use only. |

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