

| 货号 | HB921014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PTPRM Polyclonal Antibody (HB921014) is a rabbit polyclonal antibody detecting PTPRM in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTPRM (Thr1197-Ser1403). | ||||||||
| 靶标 | Protein-tyrosine phosphatase mu, R-PTP-mu, PTPRL1, PTPRM, Receptor-type tyrosine-protein phosphatase mu | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P28827 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Receptor-type tyrosine-protein phosphatase mu (PTPRM) is a ~163 kDa protein. Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function. 1. Zondag, GC. et al. (2000) The Journal of biological chemistry 275, 11264-9. PMID: 10753936 2. Aricescu, AR. et al. (2007) Science (New York, N.Y.) 317, 1217-20. PMID: 17761881 3. Kim, WK. et al. (2011) Molecular biology of the cell 22, 4883-91. PMID: 21998202 | ||||||||
| Note | For research use only. |

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