

| 货号 | HW659014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PPM1A Polyclonal Antibody (HW659014) is a rabbit polyclonal antibody detecting PPM1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human PPM1A (Gly2-Trp382). | ||||||||
| 靶标 | Protein phosphatase 2C isoform alpha, PPPM1A, Protein phosphatase 1A, Protein phosphatase IA, PP2C-alpha, PPM1A | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P35813 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein phosphatase 1A (PPM1A) is a ~42 kDa protein. Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. | ||||||||
| Note | For research use only. |

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