Anti-p21/CDKN1A Polyclonal Antibody (HW549014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HW549014

品牌

abinScience

描述

Anti-p21/CDKN1A Polyclonal Antibody (HW549014) is a rabbit polyclonal antibody detecting CDKN1A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CDKN1A (Met1-Pro164).

靶标

CDKN1, MDA-6, Cyclin-dependent kinase inhibitor 1, CIP1, WAF1, CDKN1A, p21, PIC1, Melanoma differentiation-associated protein 6, MDA6, SDI1, CDK-interacting protein 1, CAP20

纯化方式

Purified by antigen affinity column.

Accession号

P38936

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cyclin-dependent kinase inhibitor 1 (p21/CDKN1A) is a ~18 kDa protein. Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1.

1. LaBaer, J. et al. (1997) Genes & development 11, 847-62. PMID: 9106657

2. Ducoux, M. et al. (2001) The Journal of biological chemistry 276, 49258-66. PMID: 11595739

Note

For research use only.

图片

参考文献

产品说明书

Anti-p21/CDKN1A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-p21/CDKN1A Polyclonal Antibody (HW549014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-p21/CDKN1A Polyclonal Antibody (HW549014)

概述

图片

参考文献

产品说明书

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