Anti-WNT5A Polyclonal Antibody (MW294014)

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概述
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参考文献
产品说明书

概述

货号

MW294014

品牌

abinScience

描述

Anti-WNT5A Polyclonal Antibody (MW294014) is a rabbit polyclonal antibody detecting WNT5A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Alopias vulpinus, and Ambystoma mexicanum.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Mouse WNT5A (Ile62-Lys380).

靶标

Protein Wnt-5a, WNT5A

纯化方式

Purified by antigen affinity column.

Accession号

P22725

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Protein Wnt-5a (WNT5A) is a ~42 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation.

1. Kurayoshi, M. et al. (2007) The Biochemical journal 402, 515-23. PMID: 17117926

2. Mikels, AJ. et al. (2006) PLoS biology 4, e115. PMID: 16602827

3. Yamaguchi, TP. et al. (1999) Development (Cambridge, England) 126, 1211-23. PMID: 10021340

Note

For research use only.

图片

参考文献

产品说明书

Anti-WNT5A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-WNT5A Polyclonal Antibody (MW294014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-WNT5A Polyclonal Antibody (MW294014)

概述

图片

参考文献

产品说明书

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