

| 货号 | HW677014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PTGDS Polyclonal Antibody (HW677014) is a rabbit polyclonal antibody detecting PTGDS in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.
Highlights
| ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTGDS (Pro32-Gln190). | ||||||||
| 靶标 | Prostaglandin-H2 D-isomerase, PGDS2, PGD2 synthase, Prostaglandin-D2 synthase, PGDS, Cerebrin-28, L-PGDS, PDS, Beta-trace protein, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, PTGDS | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P41222 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Prostaglandin-H2 D-isomerase (PTGDS) is a ~21 kDa protein. Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. 1. Zhou, Y. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 4668-77. PMID: 20667974 2. Tokugawa, Y. et al. (1998) Biology of reproduction 58, 600-7. PMID: 9475419 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理