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Anti-PTGDS Polyclonal Antibody (HW677014)

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概述
货号HW677014
品牌abinScience
描述
Anti-PTGDS Polyclonal Antibody (HW677014) is a rabbit polyclonal antibody detecting PTGDS in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human PTGDS (Pro32-Gln190).
靶标Prostaglandin-H2 D-isomerase, PGDS2, PGD2 synthase, Prostaglandin-D2 synthase, PGDS, Cerebrin-28, L-PGDS, PDS, Beta-trace protein, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, PTGDS
纯化方式Purified by antigen affinity column.
Accession号P41222
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Prostaglandin-H2 D-isomerase (PTGDS) is a ~21 kDa protein. Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

1. Zhou, Y. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 4668-77. PMID: 20667974
2. Tokugawa, Y. et al. (1998) Biology of reproduction 58, 600-7. PMID: 9475419
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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