Anti-SOX9 Polyclonal Antibody (HW480014)

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概述
图片
参考文献
产品说明书

概述

货号

HW480014

品牌

abinScience

描述

Anti-SOX9 Polyclonal Antibody (HW480014) is a rabbit polyclonal antibody detecting SOX9 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Callithrix jacchus, and Dog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human SOX9 (Met1-Lys151).

靶标

Transcription factor SOX-9, SOX9

纯化方式

Purified by antigen affinity column.

Accession号

P48436

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Transcription factor SOX-9 (SOX9) is a ~56 kDa protein. Transcription factor that plays a key role in chondrocytes differentiation and skeletal development. Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6. Also binds to some promoter regions. Plays a central role in successive steps of chondrocyte differentiation. Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes.

1. Matsushita, M. et al. (2013) American journal of medical genetics. Part A 161A, 2528-34. PMID: 24038782

2. Südbeck, P. et al. (1996) Nature genetics 13, 230-2. PMID: 8640233

Note

For research use only.

图片

参考文献

产品说明书

Anti-SOX9 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SOX9 Polyclonal Antibody (HW480014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SOX9 Polyclonal Antibody (HW480014)

概述

图片

参考文献

产品说明书

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