

| 货号 | HW356014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-LSS Polyclonal Antibody (HW356014) is a rabbit polyclonal antibody detecting LSS in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human LSS (Asp388-Pro549). | ||||||||
| 靶标 | OSC, Lanosterol synthase, hOSC, Oxidosqualene--lanosterol cyclase, 2, 3-epoxysqualene--lanosterol cyclase, LSS | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P48449 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lanosterol synthase (LSS) is a ~83 kDa protein. Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. 1. Ruf, A. et al. (2004) Biochemical and biophysical research communications 315, 247-54. PMID: 14766201 2. Zhao, L. et al. (2015) Nature 523, 607-11. PMID: 26200341 3. Baker, CH. et al. (1995) Biochemical and biophysical research communications 213, 154-60. PMID: 7639730 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-LSS polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate



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