

| 货号 | HW402014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-EFNB2 Polyclonal Antibody (HW402014) is a rabbit polyclonal antibody detecting EFNB2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human EFNB2 (Ile28-Ala229). | ||||||||
| 靶标 | HTK ligand, EPH-related receptor tyrosine kinase ligand 5, LERK5, Ephrin-B2, HTK-L, EFNB2, EPLG5, HTKL, LERK-5 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P52799 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ephrin-B2 (EFNB2) is a ~36 kDa protein. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. | ||||||||
| Note | For research use only. |

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