

| 货号 | HW432014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-THOP1 Polyclonal Antibody (HW432014) is a rabbit polyclonal antibody detecting THOP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human THOP1 (Asn451-Thr597). | ||||||||
| 靶标 | Thimet oligopeptidase, THOP1, MP78, Endopeptidase 24.15 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P52888 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Thimet oligopeptidase (THOP1) is a ~78 kDa protein. Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1. 1. Lim, EJ. et al. (2007) The Journal of biological chemistry 282, 9722-9732. PMID: 17251185 2. Thompson, A. et al. (1995) Biochemical and biophysical research communications 213, 66-73. PMID: 7639763 | ||||||||
| Note | For research use only. |

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