Anti-CDC42 Polyclonal Antibody (HX069014)

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100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HX069014

品牌

abinScience

描述

Anti-CDC42 Polyclonal Antibody (HX069014) is a rabbit polyclonal antibody detecting CDC42 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Aedes aegypti.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CDC42 (Met1-Cys188).

靶标

CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog

纯化方式

Purified by antigen affinity column.

Accession号

P60953

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cell division control protein 42 homolog (CDC42) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration.

1. Oceguera-Yanez, F. et al. (2005) The Journal of cell biology 168, 221-32. PMID: 15642749

2. Modzelewska, K. et al. (2006) The Journal of biological chemistry 281, 37527-35. PMID: 17038317

3. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693

4. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216

5. Majmundar, AJ. et al. (2021) Science advances 7. PMID: 33523862

6. Schlam, D. et al. (2015) Nature communications 6, 8623. PMID: 26465210

7. Ninomiya, K. et al. (2021) Journal of cell science 134. PMID: 33310911

Note

For research use only.

图片

参考文献

产品说明书

Anti-CDC42 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CDC42 Polyclonal Antibody (HX069014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CDC42 Polyclonal Antibody (HX069014)

概述

图片

参考文献

产品说明书

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