

| 货号 | HX133014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-FKBP1A Polyclonal Antibody (HX133014) is a rabbit polyclonal antibody detecting FKBP1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human FKBP1A (Gly2-Glu108). | ||||||||
| 靶标 | PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Calstabin-1, FKBP-1A, FKBP1, FKBP-12, Rotamase, FK506-binding protein 1A, Immunophilin FKBP12, FKBP12, FKBP1A, 12 kDa FKBP, 12 kDa FK506-binding protein | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P62942 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Peptidyl-prolyl cis-trans isomerase FKBP1A is a ~11 kDa protein. Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||||||||
| Note | For research use only. |

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