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Anti-Human Siglec-8 Recombinant Antibody (SAA0177) (HP983107)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HP983107
品牌abinScience
种属反应性Human
应用FCM, WB
同种型IgG1, kappa
克隆号SAA0177
靶标SAF2, Sialoadhesin family member 2, SAF-2, Siglec-8, SIGLEC8, Sialic acid-binding Ig-like lectin 8
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9NYZ4
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Sialic acid-binding Ig-like lectin 8 (SIGLEC8/SAF-2) is a ~54 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose.

1. Floyd, H. et al. (2000) The Journal of biological chemistry 275, 861-6. PMID: 10625619
2. Kikly, KK. et al. (2000) The Journal of allergy and clinical immunology 105, 1093-100. PMID: 10856141
3. Pröpster, JM. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E4170-9. PMID: 27357658
NoteFor research use only.
图片
  • Bioactivity

    SEC-HPLC detection for Anti-Human SIGLEC8/SAF-2 Antibody (ABS1401).

  • Western blot

    Western blot analysis was performed using anti-SIGLEC8/SAF-2 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human SIGLEC8/SAF-2 (Catalog No: HP983011)
    Lane 2: negative control

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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