Anti-Human Siglec-10 Recombinant Antibody (S10-A) (HV244107)

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货号	HV244107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	S10-A
靶标	SIGLEC10, Siglec-10, Sialic acid-binding Ig-like lectin 10, Siglec-like protein 2, SLG2
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q96LC7
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Sialic acid-binding Ig-like lectin 10 (SIGLEC10/SLG2) is a ~76 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, seems to act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Involved in negative regulation of B-cell antigen receptor signaling. 1. Munday, J. et al. (2001) The Biochemical journal 355, 489-97. PMID: 11284738 2. Kitzig, F. et al. (2002) Biochemical and biophysical research communications 296, 355-62. PMID: 12163025 3. Zhang, P. et al. (2015) The Journal of surgical research 194, 107-13. PMID: 25450598
Note	For research use only.

Bioactivity

Detects SIGLEC10/SLG2 in indirect ELISAs.

产品说明书

Anti-Human Siglec-10 Recombinant Antibody (S10-A).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Human Siglec-10 Recombinant Antibody (S10-A) (HV244107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Siglec-10 Recombinant Antibody (S10-A) (HV244107)

概述

图片

参考文献

产品说明书

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