Anti-Human ROR1 Recombinant Antibody (SAA0140) (HX065107)

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货号	HX065107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, Kappa
克隆号	SAA0140
经测试应用	FCM
靶标	Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1, UC-961
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q01973
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443 2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350 3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human ROR1 antibody. Human CACO-2 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human ROR1 antibody monoclonal antibody (Catalog # HX065107 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414 ) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human ROR1 Recombinant Antibody (SAA0140).pdf

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Anti-Human ROR1 Recombinant Antibody (SAA0140) (HX065107)

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Anti-Human ROR1 Recombinant Antibody (SAA0140) (HX065107)

概述

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参考文献

产品说明书

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