Anti-Human Perforin Recombinant Antibody (SAA0104) (HB886107)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

货号	HB886107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	SAA0104
靶标	Cytolysin, Perforin-1, Lymphocyte pore-forming protein, PFP, PRF1, P1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P14222
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Perforin-1 is a ~61 kDa protein. Pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by mediating the passage and uptake of cytotoxic granzymes. 1. Praper, T. et al. (2011) The Journal of biological chemistry 286, 2946-55. PMID: 20889983 2. Law, RH. et al. (2010) Nature 468, 447-51. PMID: 21037563 3. Stewart, SE. et al. (2014) The Journal of biological chemistry 289, 9172-81. PMID: 24558045 4. Vergelli, M. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 2756-61. PMID: 9058810 5. Ando, K. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 5283-91. PMID: 9164947 6. Thiery, J. et al. (2010) Blood 115, 1582-93. PMID: 20038786 7. Czystowska, M. et al. (2010) Journal of molecular medicine (Berlin, Germany) 88, 577-88. PMID: 20225066 8. Zhou, Z. et al. (2020) Science (New York, N.Y.) 368. PMID: 32299851
Note	For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human Perforin Antibody (SAA0104)

产品说明书

Anti-Human Perforin Recombinant Antibody (SAA0104).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Perforin Recombinant Antibody (SAA0104) (HB886107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Perforin Recombinant Antibody (SAA0104) (HB886107)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价