Anti-Human LGR4 Recombinant Antibody (SAA0107) (HV980107)

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货号	HV980107
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, IHC, WB
同种型	IgG1
克隆号	SAA0107
靶标	GPR48, Leucine-rich repeat-containing G-protein coupled receptor 4, LGR4, G-protein coupled receptor 48, RHJ50601
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9BXB1
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) is a ~104 kDa protein. Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo.
Note	For research use only.

Bioactivity

SEC-HPLC detection for Anti-Human LGR4 Antibody (ABS0206).

产品说明书

Anti-Human LGR4 Recombinant Antibody (SAA0107).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human LGR4 Recombinant Antibody (SAA0107) (HV980107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LGR4 Recombinant Antibody (SAA0107) (HV980107)

概述

图片

参考文献

产品说明书

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