Anti-Human CD40 Ligand/TNFSF5 Recombinant Antibody (5C8) (HB199207)

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货号	HB199207
品牌	abinScience
种属反应性	Human
应用	FCM, IHC, WB
同种型	IgG1, kappa
克隆号	5C8
靶标	sCD40L, Tumor necrosis factor ligand superfamily member 5, T-cell antigen Gp39, CD40L, TNFSF5, CD154, CD40-L, TNF-related activation protein, CD40 ligand, CD40LG, TRAP
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P29965
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	CD40 ligand (CD154/CD40L) is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Graf, D. et al. (1992) European journal of immunology 22, 3191-4. PMID: 1280226 2. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 3. Blotta, MH. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 156, 3133-40. PMID: 8617933 4. Mikolajczak, SA. et al. (2004) The Journal of experimental medicine 199, 1025-31. PMID: 15067037
Note	For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human CD154/CD40LG/TNFSF5 Antibody (5C8)

产品说明书

Anti-Human CD40 Ligand/TNFSF5 Recombinant Antibody (5C8).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human CD40 Ligand/TNFSF5 Recombinant Antibody (5C8) (HB199207)

概述

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参考文献

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重组蛋白

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实验相关试剂

Anti-Human CD40 Ligand/TNFSF5 Recombinant Antibody (5C8) (HB199207)

概述

图片

参考文献

产品说明书

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