Anti-Human CD160 Reference Antibody (H7) (HF985107)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

货号	HF985107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG1, kappa
克隆号	H7
靶标	Natural killer cell receptor BY55, CD160 antigen, CD160, BY55
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	O95971
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	CD160 antigen is a ~19 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. In the context of acute viral infection, recognizes HLA-C and triggers NK cell cytotoxic activity, likely playing a role in anti-viral innate immune response. On CD8+ T cells, binds HLA-A2-B2M in complex with a viral peptide and provides a costimulatory signal to activated/memory T cells. 1. Nikolova, M. et al. (2002) International immunology 14, 445-51. PMID: 11978774 2. Rabot, M. et al. (2007) International immunology 19, 401-9. PMID: 17307798 3. Giustiniani, J. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 182, 63-71. PMID: 19109136 4. Le Bouteiller, P. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 16963-8. PMID: 12486241 5. Agrawal, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 1223-6. PMID: 9973372 6. Viganò, S. et al. (2014) PLoS pathogens 10, e1004380. PMID: 25255144 7. Fons, P. et al. (2006) Blood 108, 2608-15. PMID: 16809620 8. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050
Note	For research use only.

Bioactivity

Detects Human CD160 in indirect ELISAs.
Flow-cytometry

Flow-cytometry using anti-human CD160 antibody.CD160 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD160 antibody monoclonal antibody (Catalog # HF985107 ,Green Histogram) at a concentration of 5 ug/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human CD160 Reference Antibody (H7).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD160 Reference Antibody (H7) (HF985107)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD160 Reference Antibody (H7) (HF985107)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价