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Anti-Human DPP4/CD26 Recombinant Antibody (SAA0009) (HB015107)

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概述
货号HB015107
品牌abinScience
种属反应性Human
应用FCM
同种型IgG2b, kappa
克隆号SAA0009
靶标TP103, Dipeptidyl peptidase IV, ADABP, Dipeptidyl peptidase 4, CD26, DPP4, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase IV membrane form, DPP IV, ADCP2, Adenosine deaminase complexing protein 2, ADCP-2, T-cell activation antigen CD26
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P27487
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Dipeptidyl peptidase 4 (CD26/DPP4) is a ~88 kDa protein. Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM.

1. Ikushima, H. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8439-44. PMID: 10900005
2. Durinx, C. et al. (2000) European journal of biochemistry 267, 5608-13. PMID: 10951221
3. Ginés, S. et al. (2002) The Biochemical journal 361, 203-9. PMID: 11772392
4. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217
5. Aertgeerts, K. et al. (2004) Protein science : a publication of the Protein Society 13, 145-54. PMID: 14691230
9. Davoodi, J. et al. (2007) Proteomics 7, 2300-10. PMID: 17549790
NoteFor research use only.
图片
  • Bioactivity

    SEC-HPLC detection for Anti-Human CD26/DPP4 Antibody (ABS0753).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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