Anti-Human LAIR1 Recombinant Antibody (LA-94) (HV765107)

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货号	HV765107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG2a, kappa
克隆号	LA-94
靶标	Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, LAIR1, CD305
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q6GTX8
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Leukocyte-associated immunoglobulin-like receptor 1 (CD305/LAIR1) is a ~31 kDa protein. Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta.
Note	For research use only.

Western blot

Western blot analysis was performed using anti-CD305/LAIR1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD305/LAIR1 (Catalog No: HV765011)
Lane 2: negative control
Bioactivity

Detects recombinant CD305 (Catalog No: HV765011) in indirect ELISA.

产品说明书

Anti-Human LAIR1 Recombinant Antibody (LA-94).pdf

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Anti-Human LAIR1 Recombinant Antibody (LA-94) (HV765107)

概述

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Anti-Human LAIR1 Recombinant Antibody (LA-94) (HV765107)

概述

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参考文献

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