Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (1121B) (HW338107)

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货号	HW338107
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG2a, kappa
克隆号	1121B
经测试应用	FCM
靶标	FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P35968
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~151 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).
Note	For research use only.

Bioactivity

SEC-HPLC detection for Anti-Human CD309/KDR/VEGFR-2 Antibody (1121B).
Flow Cytometry

Flow-cytometry using anti-human CD309 antibody.CD309 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD309 antibody monoclonal antibody (Catalog # HW338107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human CD309 antibody.HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD309 antibody monoclonal antibody (Catalog # HW338107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (1121B).pdf

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Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (1121B) (HW338107)

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图片

参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (1121B) (HW338107)

概述

图片

参考文献

产品说明书

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