Anti-Human CRACC/SLAMF7 Recombinant Antibody (ABBV-383) (HV217207)

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货号	HV217207
品牌	abinScience
种属反应性	Human
应用	FCM
同种型	IgG2a, kappa
克隆号	ABBV-383
经测试应用	FCM
靶标	SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9NQ25
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. 1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418 2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536 3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771 4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human CD319 antibody.CD319 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD319 antibody monoclonal antibody (Catalog # HV217207 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human CRACC/SLAMF7 Recombinant Antibody (ABBV-383).pdf

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Anti-Human CRACC/SLAMF7 Recombinant Antibody (ABBV-383) (HV217207)

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参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Human CRACC/SLAMF7 Recombinant Antibody (ABBV-383) (HV217207)

概述

图片

参考文献

产品说明书

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