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Anti-Human CRACC/SLAMF7 Recombinant Antibody (Luc63) (HV217107)

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  • 100ug
数量:
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概述
货号HV217107
品牌abinScience
种属反应性Human
应用ELISA, FCM, IF, IP, WB
同种型IgG1, kappa
克隆号Luc63
靶标SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9NQ25
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B.

1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418
2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536
3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771
4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD319/SLAMF7 Antibody (Luc63)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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