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Anti-Human TIM-1/KIM-1/HAVCR Recombinant Antibody (2.59#) (HV277107)

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概述
货号HV277107
品牌abinScience
种属反应性Human
应用FCM
同种型IgG1, kappa
克隆号2.59#
靶标TIM, Kidney injury molecule 1, T-cell immunoglobulin mucin receptor 1, KIM1, KIM-1, TIM1, TIMD1, HAVCR1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell membrane protein 1, CD365, Hepatitis A virus cellular receptor 1, HAVcr-1, TIMD-1, TIM-1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q96D42
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Hepatitis A virus cellular receptor 1 (CD365/KIM-1) is a ~39 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation.

1. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780
2. Ichimura, T. et al. (2008) The Journal of clinical investigation 118, 1657-68. PMID: 18414680
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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