Anti-Human CD37 Recombinant Antibody (SAA0012) (HY564207)

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50ug
100ug

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货号	HY564207
品牌	abinScience
种属反应性	Human
应用	ELISA, FCM, IHC, WB
同种型	IgG1, kappa
克隆号	SAA0012
经测试应用	WB, FCM
靶标	CD37, Tspan-26, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P11049
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role essential for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT. 1. Lapalombella, R. et al. (2012) Cancer cell 21, 694-708. PMID: 22624718 2. de Winde, CM. et al. (2016) The Journal of clinical investigation 126, 653-66. PMID: 26784544 3. Meyer-Wentrup, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 154-62. PMID: 17182550
Note	For research use only.

Flow Cytometry

Flow-cytometry using anti-human CD37 antibody. Human RPMI-8226 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD37 antibody monoclonal antibody (Catalog # HY564207 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-IL23A monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL23A (Catalog No: HV466011)
Lane 2: negative control

产品说明书

Anti-Human CD37 Recombinant Antibody (SAA0012).pdf

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Anti-Human CD37 Recombinant Antibody (SAA0012) (HY564207)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD37 Recombinant Antibody (SAA0012) (HY564207)

概述

图片

参考文献

产品说明书

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